The understanding of Health, and healing, as a concern within the field of what we call, today, the Humanities, has dominated from the dawn of human societies to the 19th century. Contrary to a current public perception, Medicine was never understood, not only in the East but also in the West, as primarily a set of techniques. Meaning, purpose and holistic understanding of the patients and of the management of diseases (such as pandemic processes) was dominantly understood as an art. Certainly, scientific advances, namely from modernity onwards, allowed to couple this approach with a growing understanding of physiology and, at large, physical, chemical and biological process, which led to the healing of several previously deadly diseases, increased life expectancy and diminished death at birth. It is by no coincidence that Medicine faculties remained separate from Sciences schools, and even, occasionally, integrated in “Classical Universities” instead of migrating to new “Technological Universities”. However, the acceleration of technological advances and the turn towards quantification of results, themselves not to be blamed, entailed a deep crisis of the Humanities since after WWII, slowly reifying natural sciences, and moreover technologies and solutions, detaching them from intangible purposes and the understanding of dilemmas. The current growing ethical concerns in medicine, in the public sphere, echo a never interrupted reflection of the Humanities, and express a new social awareness of the shortcomes of the positivist STEM approach. But the contribution of the Humanities goes far beyond, and building the appropriate tools to face new health management concerns (e.g. on managing the next pandemic crisis or convincing people to take vaccines) requires resuming older concepts from different traditions, merging them in order to offer society new insights, within a globalized debate which is dominated by uncertainty.